DIRECT ENGULFMENT OF SYNAPSES BY OVERACTIVATED MICROGLIA DUE TO CADMIUM EXPOSURE AND THE PROTECTIVE ROLE OF NRF2

Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2

Cadmium (Cd), a notorious environmental pollutant, has been linked to neurological disorders, but the underlying mechanism remains elusive.We aimed to explore the role of microglia in Cd-induced synaptic damages at DULSE LEAVES environmentally relevant doses and whether microglia directly engulf synaptic structures.Nrf2 is deeply implicated in the

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Impaired Myocardial Perfusion from Persistent Mammary Side Branches: A Role for Functional Imaging and Embolization

The Axes diagnosis and management of ischemic symptoms in patients after coronary artery bypass surgery can be challenging.It has been hypothesized that persistent branches of the internal mammary artery can divert flow from the left anterior descending artery and cause symptoms.We present a case in which successful Shirts coil embolization of a si

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Class I HLA Allele Predicted Restricted Antigenic Coverages for Spike and Nucleocapsid Proteins Are Associated With Deaths Related to COVID-19

The world is dealing with one of the worst pandemics ever.SARS-CoV-2 is the etiological agent of COVID-19 that has already spread to more than 200 countries.However, infectivity, OLIVE severity, and mortality rates do not affect all countries equally.Here we consider 140 HLA alleles and extensively investigate the landscape of 3,723 potential HLA-I

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